B0008377 Clostridium difficile
Credit: David Goulding, Wellcome Trust Sanger Institute. Wellcome Images
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Clostridium difficile is a major cause of antibiotic-associated diarrheal disease. Part of the reason for it’s persistence in the hospital environment has been ineffective disinfection regimes which have enabled the highly resistant spores to accelerate host transmission. This image illustrates how effectively the vegetative core is protected by three clearly defined coats 100nm thick and an exosporium.
Transmission electron micrograph
2011 Published: –

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