B0009547 Human prion protein structure, illustration
Credit: Anna Tanczos. Wellcome Images
Illustration of human prion protein variant V129 based on the X-ray crystallography structure (PDB ID: 3HAK; Lee et al (2010) Embo J. 29: 251-262). Prion proteins are responsible for transmissible spongiform encephalopathies (TSE) in mammals. They are infectious abnormal proteins which accumulate in the brain and cause disease such as Creutzfeldt-Jakob disease (CJD) and kuru in humans, and bovine spongiform encephalopathy (BSE or mad cow disease) in cattle.
Digital artwork/Computer graphic
2014 Published: –

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